Thursday, October 31, 2019

Issues Related to Communication in Contemporary Society Essay

Issues Related to Communication in Contemporary Society - Essay Example Culture has a great impact on communication in society for a variety of reasons. Among these is that culture provides the information that will help in understanding each other hence the eventual successful communication (Giri, 1). Culture in brief can be defined as all the activities and events that make up the life of a people who stay at certain geographical area. Through culture people are able to socialise and in this it provides the information and tools that will be in communication. Culture normally gives the norms and habits that are acceptable. In order to fit into a society one has to be able to be as everyone else. By this they have to adopt all the beliefs and norms in the society. Failure to this will lead to one being treated as an outsider and in such instances the information availed becomes limited and reduces the chances of being able to communicate. In addition without socialization, the ability to communicate may be hampered due to being unable to understand the practices of a people hence limiting the level of communication that can take place (Hauben, 2). How Culture Impacts on Communication According to Giri (1), to every culture there a certain behaviour that the males and females depending on the age will be prescribed. Hence according to the culture there will be certain institutional cultures that will be allowed along with roles in gender. Failure to observe this can lead to alienation by the society. Hence in order for an individual to properly communicate in society there is the need to act and behave within these standards in order to be accepted. Among this include the communication aspect, in this there are topics and approaches that certain genders and ages have to adopt. This will clearly impact on the level of communication as they will consider the topics and people to talk to. In addition, depending on the culture one will develop views that may be associated to either the culture or political background and this will affe ct the approach to various issues. The conversational styles learned from the culture in the society are another factor to consider as it will impact on the way one talks and acts in various situations. The culture also shapes the kind of person will become. Through to the culture and values that are practiced the personality of a person becomes shaped. In this they end having low self-esteem or the level of disclosure will also be impacted. Through this the person will limit the amount of information that they give out and receive. In doing so, the ability to communicate is hampered as no free flow of information will be able to take place. Another issue about culture is that it provides the tool that is used commonly on the day-to-day communication. By this it implies the language that is used. Each society has a culture and in this culture will be the language that is used. If one does not belong to the society, they will definitely not know the language in use and in this will b ring out the biggest challenge to communication. Hence the need to know the language in use cannot be overemphasised (Jandt, 294). Novinger (1), states that in a culture there are a certain pattern of habits and bodily behaviours that help in the interpersonal behaviours. Besides, there also the various parameters that are used in the context of interpersonal interaction. Most of the parameters

Tuesday, October 29, 2019

Critical Exploration by Using Gibbs Model Essay - 1

Critical Exploration by Using Gibbs Model - Essay Example A 2nd-year student is practicing as a nurse at a hospital. The girl is very sweet, caring and loving towards her patients. She is always up to help other staff members with a smile. However, she has trouble in being able to prioritize and co-ordinate the attention needs of patients that we both have duties for. She also seems to lack confidence in her nursing skills and has teething troubles in linking theory to practice.  The result of the study reveals that the girl needs to understand what she wants to achieve. In this case, it is very obvious what she wants to achieve but she is not sure how to achieve it. The consequences of not prioritizing her duties make her more frustrated and annoyed and at the end of the day, nothing has achieved the way she wants to achieve it. It is also expected that some of the patients end up saying that want a different nurse to take care of them. As frequently does not complete the instructions given to her by these other staff and leaves the care given to patients unfinished. At the second stage of the Gibbs model, it can be said that the girl needs this practice because she wants to end up at some great hospital but if she continues to give such results that are poor practices, poorly set priorities it is giving out a bad image of her and the further recommendation for her are at stake. The student for sure feels the responsibility she has but as an amateur, she is finding difficulties in some areas and usually panics. She needs someone to guide her for at least a week so that she improves her practice and give satisfying results. However, the good part is the girl is willing to help. She wants to be someone and never refuses to work. In short, the girl has proved to be a very hard working dedicated worker but needs to manage things a little more. Most nursing students will attain the expertise criterions they need to catalog but tutors may be faced with an apprentice whose  presentation is scrawny.

Sunday, October 27, 2019

Role of Medicinal Plants for Health

Role of Medicinal Plants for Health General The use of natural products with therapeutic properties is as ancient as human civilization. For a very long time, mineral, plant and animal products were the main sources of drugs [1].The use of complementary medicine to alleviate and improve health conditions is increasing in developed countries [2]. New medicinal plants from different parts of the world are being investigated with this purpose in mind [3]. Although the utilization of botanicals has increased in the western world, there is a lack of information about mechanisms of action and potential differences among species within the same genus [4]. Now-a-days, several plants have been identified for their anticancer and anti-inflammatory compounds. Scientific experiments on the anticancer properties of plants and their components have been detected. Herbal medicines have been the basis of treatment and cure for various diseases and physiological conditions in traditional methods practiced such as ayurveda, unani and siddha. However no systematic studies were conducted to evaluate the efficacy and safety of the formulations from the plant were undertaken. Also no attempts were made to isolate and identify the active principles involved in these effects [5]. As an evolutionary response plants were obliged to produce and store a wide range of organic molecules. These substances are usually termed as secondary metabolites (SM). Some of these compounds are involved in the survival of the plants as a defense mechanism against natural enemies. Many SM could actively interact with targets in the human body inducing a bioactivity of interest [6]. The bioactive compounds of medicinal plants are used as anti-diabetic, chemotherapeutic, anti-inflammatory, anti-arthritic agents where no satisfactory cure is present in modern medicines. The use of plants for medicinal purposes dates back to antiquity because they contain components of therapeutic value [7]. Medicinal plants are cheaper and more accessible to most of the population in the world. The acceptance of traditional medicine as an alternative form of health care and the development of microbial resistance to the available antibiotics has led researchers to investigate various therapeutic uses of medicinal plants [8]. Therefore, the quest for plants with medicinal properties continues to receive attention as scientists are in need of plants, particularly of ethno botanical significance for a complete range of biological activities, which ranges from antibiotic to anti-cancerous [9]. Bangladesh features a sub-tropical climate and low-lying landmass largely adjacent to extensive river deltas. The country comprises very fertile soils and is home to some rare ecosystems such as the Sundarbans mangrove forests. Given the fertile plains and high population density, the indigenous vegetation has mostly given way to cropland and extensive cultivation. Today, almost 60% of the landmass is used for farming, which is a global maximum value. However, originally large parts of Bangladesh featured tropical forests and marshy jungle with highly bio-diverse flora being also an excellent source for medicinal plants. The Bangladeshi traditional medicine is a unique conglomerate of different ethnomedical influences. Due to the geographic location and sociocultural characteristics of the country, it involves traditionally rooted elements influenced by local indigenous people and close-by Indian Ayurveda and Unani medicine [10, 11]. Given its inexpensive, easily accessible and well-established health services, the use of traditional medicine is an integral part of public health services in Bangladesh with its providers being deeply embedded within the local community [12-14]. Recent data suggest that the utilization of traditional medicine health services in Bangladesh is widespread [15] and plays a crucial role in providing health care for poor people, people in rural areas and for tribal people [16]. Antioxidant and anti-inflammatory activities of medicinal plants The anti-oxidative activity has been confirmed contributing kinds of cancer and inflammatory preventions for its multiple functional roles. The production of oxidants is a typical event associated with aerobic metabolism. When oxygen is supplied in excess or its reduction is insufficient, reactive oxygen species or free radicals such as superoxide anions, hydroxyl radicals and hydrogen peroxide are generated [17]. Accumulation of the free radicals in body organs or tissues can cause oxidative damage to biomolecules and membranes of cell, eventually leading to many chronic diseases, such as inflammatory, cancer, diabetes, aging, cardiac dysfunction and other degenerative diseases [18]. In the last 50 years, antioxidant and anti-inflammatory activities of extracts from medicinal or food plants have been extensively investigated. Many pharmacological studies have shown that extracts of some antioxidant plant possess anti-inflammatory, anti-allergic, anti-tumor, anti-bacterial, anti-muta genic and anti-viral activities to a greater or lesser extent. Researchers reported that intake of fruits, vegetables and other foods having high antioxidant activity has been associated with reduced risks of cancer, cardiovascular disease, diabetes and other diseases [17]. Trouillas et al. investigated the antioxidant, anti-inflammatory and anti-proliferative properties of sixteen French herbal tea and found some herbs exhibited high antioxidant, anti-inflammatory and anti-proliferative activities [19]. Antioxidant activities in twenty traditional anti-inflammatory herbs extracts were investigated. The results suggested that the anti-inflammatory activities of these extracts could be explained, at least in part, by their antioxidant properties [20]. Free radicals liberated from phagocyte cells are important in inflammatory processes, because they are implicated in the activation of nuclear factor kB, which induces the transcription of inflammatory cytokines and cyclooxygenase-2 [21 ]. Free radicals and oxidative stress Reactive oxygen species (ROS) is a term that encompasses all highly reactive, oxygen containing molecules, including free radicals. Types of ROS include the hydroxyl radical, the superoxide anion radical, hydrogen peroxide, singlet oxygen, nitric oxide radical, hypochlorite radical, and various lipid peroxides. All are capable of reacting with membrane lipids, nucleic acids, proteins and enzymes, and other small molecules, resulting in cellular damage. ROS are generated by a number of pathways. Most of the oxidants produced by cells occur as: A consequence of normal aerobic metabolism: approximately 90% of the oxygen utilized by the cell is consumed by the mitochondrial electron transport system. Oxidative burst from phagocytes (white blood cells) as part of the mechanism by which bacteria and viruses are killed, and by which foreign proteins (antigens) are denatured. Xenobiotic metabolism, i.e., detoxification of toxic substances. Consequently, things like vigorous exercise, which accelerates cellular metabolism; chronic inflammation, infections, and other illnesses; exposure to allergens and the presence of leaky gut syndrome; and exposure to drugs or toxins such as cigarette smoke, pollution, pesticides, and insecticides may all contribute to an increase in the bodys oxidant load [22]. Most reactive oxygen species are generated as by-products during mitochondrial electron transport. In addition ROS are formed as necessary intermediates of metal catalyzed oxidation reactions. Atomic oxygen has two unpaired electrons in separate orbits in its outer electron shell. This electron structure makes oxygen susceptible to radical formation. The sequential reduction of oxygen through the addition of electrons leads to the formation of a number of ROS including: superoxide; hydrogen peroxide; hydroxyl radical; hydroxyl ion; and nitric oxide. Free radicals and other ROS are derived either from normal essential metabolic processes in the human body or from external sources such as exposure to X-rays, ozone, cigarette smoking, air pollutants, and industrial chemicals. Free radical formation occurs continuously in the cells as a consequence of both enzymatic and non-enzymatic reactions. Enzymatic reactions, which serve as source of free radicals, include those involved in the respiratory chain, in phagocytosis, in prostaglandin synthesis, and in the cytochrome P-450 system. Free radicals can also be formed in non-enzymatic reactions of oxygen with organic compounds as well as those initiated by ionizing reactions. Some internally generated sources of free radicals are Mitochondria, Xanthine oxidase, Peroxisomes, Inflammation, Phagocytosis, Arachidonate pathways, Exercise, Ischemia/reperfusion injury etc. Some externally generated sources of free radicals are- Cigarette smoke, Environmental pollutants, Radiation, Certain drugs, pesticides, Industrial solvents, Ozone etc. Normally, cells defend themselves against ROS damage with enzymes such as alpha-1-microglobulin, superoxide dismutases, catalases, lactoperoxidases, glutathione peroxidases and peroxiredoxins. Small molecule antioxidants such as ascorbic acid (vitamin C), tocopherol (vitamin E), uric acid, and glutathione also play important roles as cellular antioxidants. In a similar manner, polyphenol antioxidants assist in preventing ROS damage by scavenging free radicals. In contrast, the antioxidant ability of the extracellular space is less e.g., the most important plasma antioxidant in humans is uric acid. Effects of ROS on cell metabolism are well documented in a variety of species. These include not only roles in apoptosis (programmed cell death) but also positive effects such as the induction of host defense genes and mobilization of ion transport systems. This implicates them in control of cellular function. In particular, platelets involved in wound repair and blood homeostasis release ROS to recruit additional platelets to sites of injury. These also provide a link to the adaptive immune system via the recruitment of leukocytes. Reactive oxygen species are implicated in cellular activity to a variety of inflammatory responses including cardiovascular disease. They may also be involved in hearing impairment via cochlear damage induced by elevated sound levels, in ototoxicity of drugs such as cisplatin, and in congenital deafness in both animals and humans. ROS are also implicated in mediation of apoptosis or programmed cell death and ischemic injury. Specific examples include stroke and heart attack. All the biological molecules present in our body are at risk of being attacked by free radicals. Such damaged molecules can impair cell functions and even lead to cell death eventually resulting in diseased states. In recent years it has become apparent that the oxidation of lipids, or lipid peroxidation, is a crucial step in the pathogenesis of several disease states in adult and infant patients. Lipid peroxidation is a process generated naturally in small amounts in the body, mainly by the effect of several reactive oxygen species (hydroxyl radical, hydrogen peroxide etc.). It can also be generated by the action of several phagocytes. These reactive oxygen species readily attack the polyunsaturated fatty acids of the fatty acid membrane, initiating a self-propagating chain reaction. The destruction of membrane lipids and the end-products of such lipid peroxidation reactions are especially dangerous for the viability of cells, even tissues [23-25]. Membrane lipids present in subcellular organelles are highly susceptible to free radical damage. Lipids when reacted with free radicals can undergo the highly damaging chain reaction of lipid peroxidation (LP) leading to both direct and indirect effects. During LP a large number of toxic byproducts are also formed that can have effects at a site away from the area of generation, behaving as second messengers. The damage caused by LP is highly detrimental to the functioning of the cell [26]. Lipid peroxidation is a free radical mediated process. Initiation of a peroxidative sequence is due to the attack by any species, which can abstract a hydrogen atom from a methylene group (CH2), leaving behind an unpaired electron on the carbon atom (à ¢Ã¢â€š ¬Ã‚ ¢CH). The resultant carbon radical is stabilized by molecular rearrangement to produce a conjugated diene, which then can react with an oxygen molecule to give a lipid peroxyl radical (LOOà ¢Ã¢â€š ¬Ã‚ ¢). These radicals can further abstract hydrogen atoms from other lipid molecules to form lipid hydroperoxides (LOOH) and at the same time propagate LP further. The process of LP, gives rise to many products of toxicological interest like malondialdehyde (MDA), 4-hydroxynonenal (4-HNE) and various 2-alkenals. Isoprostanes are unique products of lipid peroxidation of arachidonic acid and recently tests such as mass spectrometry and ELISA-assay kits are available to detect isoprostanes [27]. Oxidation of proteins by ROS/RNS can generate a range of stable as well as reactive products such as protein hydroperoxides that can generate additional radicals particularly upon interaction with transition metal ions. Although most oxidized proteins that are functionally inactive are rapidly removed, some can gradually accumulate with time and thereby contribute to the damage associated with ageing as well as various diseases. Lipofuscin, an aggregate of peroxidized lipids and proteins accumulates in lysosomes of aged cells and brain cells of patients with Alzheimers disease [28]. Inflammation Inflammation is one of the body unique mechanisms that help body to protect itself against infection, burn, toxic chemicals, allergens or other noxious stimuli [29]. It is a body defense reaction in order to eliminate or limit the spread of injurious agent [30]. The process is created by immune cells invading the tissue like an army in full battle mode [31]. There are various components of inflammatory reaction that can contribute to the associated symptoms and tissue injury [30]. During inflammation, innate cells and molecules are usually stimulated to isolate, destroy infectious agents and repair tissue, or sometimes the adaptive immune system is also stimulated [32]. Consequently, the mechanism works in a cascade, where the inflammation is often triggered by circulating immune complexes that enter tissues [31]. Principally, inflammation is manifested by pain, swelling, redness band loss of function in the afflicted tissue [31, 33]. Saladin (2007) categorized process of inflammation into three major processes; mobilization of the bodys defenses, containment and destruction of pathogens, and tissue clean up and repair [34]. While Mahat and Patil (2007) classified the process into three phases; the first phase is caused by an increase in vascular permeability, the second one by infiltration of leukocytes and the third one by granuloma formation [30]. The inflammatory response is initiated by circulating proteins and blood cells when they contact invaders in the tissue. Microbial invaders that lodge in body tissue and begin to proliferated triggered inflammatory response [33]. Bacterial products interact with plasma factors and cells to produce agents that attract neutrophils to the infected area (chemotaxis). The chemotactic agents, which are part of a large family of chemokines, include a component of the complement system (C5a), histamine, kinins, leukotrienes, and polypeptides from lymphocytes, mast cells, and basophils [35]. The neutrophils also produce oxidants and release granular constituents comprising of lytic enzymes performing important role in inflammatory injury [36]. The innate immune system contributes to inflammation by activating the alternative and lechitin-binding complement pathways, attracting and activating phagocytic cells that secrete cytokines and chemokines, activating NK cells, altering vas. The result would firstly be increased in blood flow to the affected tissue which accelerates the delivery of immune system element to the site [33]. The vasodilation would later cause enlarged capillaries and lead to redness (erythema) as well as increase in temperature, which for an influx of fluid and cells, contributing to swelling [32]. Saladin (2007) explained that the increased in blood flow also washes toxin and metabolic wastes from the tissue rapidly. In addition, vasoactive chemicals cause endothelial cells of the blood capillaries to separate a little, widening the intracellular cleft between them and increasing capillary permeability that ease the movement of fluid, leukocytes, and plasma proteins from the bloodstream into the surrounding tissue [34]. In the area of injury, many of the neutrophils enter the tissues. As neutrophils encounter bacteria, they avidly phagocytize, digest and destroy them. Neutrophils also recruit macrophages and additional neutrophils by secreting cytokines [33]. Activated macrophages and T cells in the inflamed tissue also secrete cytokines called colony stimulation factors, which promotes the production of more leukocytes by the red bone marrow. Within a few hours of inflammation, neutrophilia (the rise in the neutrophil count in blood) would occur [37]. Then, the neutrophils are attracted to the endothelial surface by selectins, and they roll along it. They bind firmly to neutrophil adhesion molecules of the integrin family. They next insinuate themselves through the walls of the capillaries between endothelial cells by a process called diapedesis [35]. Leukocytes adhere loosely to the selectins and slowly tumble along the endothelium, sometimes coating it so thick that they obstruct blood flow. This adherence to the vessel wall is called margination [38]. Later, the fibrinogens are filtered into the tissue fluid clots in area adjacent to the injury, forming a sticky mesh that sequesters bacteria and other microbes [34]. This is caused by release of chemicals from tissues and migrating cells. Most strongly implicated are the prostaglandins (PGs), leukotrienes (LTs), histamine, bradykinin, platelet- activating factor (PAF) and interleukin-1 [39]. Prostaglandin is implicated in inducing the production of various chemo-attractants and pro-inflammatory cytokines [36]. Gislason (2009) mentioned that macrophages and neutrophils are responsible to secrete a number of mediators which is responsible not just for initiation, but also for progression and persistence of acute or chronic state of inflammation [31]. Finally, monocytes acts as the major agent in tissue clean up and repair. It enters the blood from the bone marrow and circulated for about 72 hours. Then, they enter the tissues and become tissue macrophage. The macrophage becomes activated by lympokines from T lymphocytes [35]. The activated macrophage migrate in respond to chemotactic stimuli and later engulf and destroy bacteria, damaged host cells, as well as dead and dying neutrophils. Besides that, it also acts as antigen presenting cells and activating specific immune response [34]. Edema may also contribute to the tissue clean up. Nitric oxide is responsible for vasodilatation, increase in vascular permeability and edema formation at the site of inflammation [36]. The swelling compresses veins and reduce venous drainage, while it forces open the valve of lympathic capillaries and promote lympathic drainage. The lymphatics can collect and remove bacteria, dead cells, proteins and tissue debris better than blood capillary can. An accumulation of dead cells of neutrophils with other debris tissue and fluid will form pus, a yellowish fluid. It may accumulate in the tissue cavity and known as abcess [32]. Pus is usually absorbed, but sometimes it may be released by its rupture. Blood platelets and the endothelial cells in an area of injury secrete platelet derived growth factor, an agent that stimulates fibroblast to multiply and synthesize collagen. Hyperemia at the same time delivers the oxygen, amino acids and other necessities of protein synthesis, while the hea t of inflamed tissue increases metabolic rate and speed of mitosis and tissue repair. The fibrin clot in inflamed tissues may provide a scaffold for tissue reconstruction [34]. In part, inflammation declines simply because the mediators of inflammation have short half-lives, are degraded after their release, and are produced in quick bursts, only as long as the stimulus persists. In addition as inflammation develops, the process also triggers a variety of stop signals that serve to actively terminate the reaction [38]. Anti-inflammatory Activity Anti-inflammatory refers to the property of a substance or treatment that reduces inflammation. Anti-inflammatory drugs make up about half of analgesics, remedying pain by reducing inflammation as opposed to opioids, which affect the central nervous system. Drugs to control inflammation When healing is complete, the inflammatory process usually subsides [32]. However, an uncontrolled and persistent inflammation that sometimes is triggered by harmless agent such pollen or by an auto immune response. It may act as an etiologic factor for many of these chronic illnesses, where it may induce, maintain or aggravate the disease [29]. As mentioned, the inflammation would occur with the presence of antigen. Thus, constant supply of antigen is available from the food or environment may leads to chronic inflammation and causes diseases such as asthma, arthritis and other autoimmune diseases [31]. In such cases, the defense reaction themselves may cause progressive tissue injury. Hence, anti-inflammatory or immunosuppressive drugs may be necessary to modulate the inflammatory process [37]. Anti-inflammatory drugs are designed to targets the inhibition of the release of these mediators to control inflammation [36]. Harvey and Champe (2008) have classified anti-inflammatory drugs into three category; Nonsteroidal anti-inflammatory drugs (NSAIDs), Cyclooxygenase-2 inhibitors (COX-2 inhibitors) and other analgesics [32]. Aspirin is a prototype of traditional NSAIDs. It works by irreversibly inhibit Cyclooxygenase 1 and 2 (COX-1 and 2) enzymes, which results in decreased formation of prostaglandin precursors [40]. Due to this mechanism of action, aspirin also cause adverse effects such as gastric hemorrhages, hypersensitivity and thrombocytopenia [41]. It is becoming a concern of healthcare providers that patients are developing intolerance from day to day. About fifteen percent of patients show intolerance with aspirin. Therefore, newer NSAIDs with greater anti-inflammatory activities are developed. However, the newer NSAIDs are considerably more expensive than aspirin and some have proved to be more toxic in the other way [32]. The second category is COX-2 inhibitor. The mechanism of action is by selectively inhibiting the activity of COX-2 enzyme that results in decreased of prostaglandin precursors [37]. Unlike aspirin, COX-2 inhibitors have an advantage by showing lower risk of developing gastrointestinal bleeding and have no significant effects on platelets [42]. However, this drug is not recommended for renal impaired patients because it may cause renal insufficiency and increase the risk of hypertension [40]. It also has some possible adverse effects recorded in Malaysian Index of Medical Specialities (MIMS) that it may cause allergic reaction, dizziness, headache, rash, upper respiratory infection and gastrointestinal disturbances such as dyspepsia, abdominal pain and diarrheas [41]. Acetaminophen is categorized under other analgesic because it has little or no anti-inflammatory activity [32]. It inhibits the synthesis of prostaglandin in the central nervous system and peripherally blocks pain impulse generations [40]. They have therapeutic advantages over narcotic analgesics which they do not cause physical dependence or tolerance and does not affect platelet function or increase blood clotting time, but it does have many of side effects similar to aspirin [42]. Rarely, skin rash and allergic reaction may appear as the side effects [41]. There are also drugs from autacoids antagonist such as antihistamines used to prevent progress of inflammation. The term antihistamine, without a modifying adjective, refers to the classic H1 receptor blockers [32]. H1 histamine antagonists drugs are develop effectively to target the receptors to treat hay fever and some skin allergies such as urticaria. H1 receptor blockers act on immunoglobulin E (IgE) antibody-sensitizing mast cell [37]. Rheumatoid arthritis is alleviated by drugs, which inhibit the cyclooxygenase enzyme and reduce synthesis of prostanoids, corticosteroids prevent the formation of both prostaglandins and leukotriens by causing the release of lipocortin that leads to inhibition of phospholipase A2 that reduces arachidonic acid release which is able to suppress the inflammation of rheumatoid arthritis and asthma [39]. Anti-cytokines therapy involving target on Interleukin-1b (IL-1b) and tumor necrosis factor-ÃŽÂ ± (TNF-ÃŽÂ ±) that stimulate synovial cells to proliferate and synthesize collagenase, leading to degradation of cartilage, stimulation of bone resorption, and inhibition of proteoglycan synthesis is another method that is effective in treating rheumatoid arthritis [32]. Despite the benefits that the drugs hold, it also carries the side effects. As a result, it may lead various unwanted effects such as to gastric lesions, allergy reactions, tolerance and dependence, as well as resistance [40, 43]. Hence, worldwide researchers are still working to produce the ideal medicines of anti-inflammatory with highest efficacy, best potency and lowest or none side effects. Description of the plant investigated Bauhinia acuminata L. is a species of flowering shrub native to tropical southeastern Asia. The exact native range is obscure due to extensive cultivation, but probably from Malaysia, Indonesia (Java, Borneo, Kalimantan, Lesser Sunda Islands), and the Philippines. It is widely cultivated throughout the tropics as an ornamental plant. It may be found as an escape from cultivation in some areas, and has become naturalized on the Cape York Peninsula, Australia [44]. Common Name Bangla: Shwet Kanchan. Malaysian: Bunga Perak. English: Dwarf White Bauhinia, White Mountain Ebony [45]. Indonesian: Panawar Saribu (Sunda Islands); Kupu-kupu (Java) Thailand: Ka Long, SomSio Burma: Mahahlegabyu India: Kaanchnaara, Kovidaara (Ayurvedic); Kachnaal (Unani); Vellaimandarai (Siddha/Tamil); Kanchan (Assam); Shwetkachnar, Kachnalsafaid (Punjab) Sri Lanka: Sudu Kobalila (Singhalese) Japan: Moku-wan-ju. Taxonomical Hierchy: Kingdom : Plantae Subkingdom : Viridaeplantae Infrakingdom : Streptophyta Division : Tracheophyta Subdivision : Spermatophytina Infradivision : Angiosperms Class : Eudicots Superorder : Rosids Order : Fabales Family : Fabaceae Subfamily : Caesalpiniaceae Genus : Bauhinia Species : B. acuminata Binomial name : Bauhinia acuminata L. Botanical Description: Fig.-1.1: Bauhinia acuminata L. tree. Bauhinia acuminata L. is a member of the Fabaceae family. It is a rapidly growing shrub that can reach up to 3m tall. It rises with several strong, smooth, upright stems with many slender branches; young twigs being pubescent. The stipules are linear-lanceolate measures 1cm long. The leaves are cordate or nearly so are the base, bilobed to about one third of their length with obtuse or acute lobes 9-11 nerve, sparsely pubescent beneath, about 10cm long and broad. The flowers appear at the extremities of the branches 3-4 in a loose bunch with white petals. Thepedicels measure 6-12mm long. The flower buds fusiform, long attenuate at the apex and 5 setaceous dents, measures 3cm long. The calyx-limb laterally splitting, spathaceous; receptacle short. The petals obovate, measure 4cm long and 2cm wide. The stamens 10 all fertile, shorter than the petals; anthers small.The ovary shortly stipitate, sparsely pubescent. The pods are linear-oblong, stipitate, measure 10cm long and 1.5cm wide, d ark brown in colour containing 10 roundish compressed seeds [46, 47]. Traditional uses of Bauhinia acuminata L. The bark and leaves in a decoction helps relieve biliousness [48]. A remedy recommended by the Indian Vaiydas [45]. In Malaysia and Indonesia the plant is used in the treatment of common cold and cough [48]. The root seems to be the part made used of by the Japanese in treating cough and cold. In India the decoction of the leaves and bark is given for allying asthmatic attack. The Indians made used of the bark and leaves in a decoction to treat stones in the bladder, venereal diseases and leprosy [45]. Amongst the Mullu kuruma tribe of Karella the decoction of the bark is used in treating urinary discharge (gonorrhea). They make use of paste of the leaves applied on the throat for throat troubles. It is applied externally to treat skin diseases [49]. The root is boiled in oil and applied to burns and pain [45]. Objective of study To evaluate the free radical scavenging and anti-inflammatory activity of Bauhinia acuminata L. bark extracts in rats. Significance of study Bauhinia acuminata L. is one of the

Friday, October 25, 2019

My Dad and Old Cars Essay -- Personal Narrative Writing

My Dad and Old Cars Some people bring home stray dogs. My father brings home stray cars. He gets emotionally attached and eventually puts them on life support. This keeps them viable long beyond the time other family members vote to pull the plug. He drives a 1968 VW van that chugs along on its third rebuilt engine. My big brother vows to bury dad in it. The 1971 VW Bug that he used for fifteen years is still operable, but since a teenager's foot went through the rusted floorboards to the street below, it's been relegated to the retirement home: his driveway. He continues paying on the life insurance policy but he has signed a "Do Not Resuscitate" waiver. My father went off to college in a 1931 Model A Ford. In the back seat of that car, on an old country road, I made love for the first time. Now it sits under a blue parachute in the driveway. Mice breed in the upholstery and the ceiling fabric hangs in shreds, but my father is convinced the car will awaken from its coma and live to cruise again. A 1960 Plymouth Valiant that drove like a tank and sounded like a B-52 suffered sudden paralysis one car-pooling morning when both front wheels turned at right angles to the frame of the car, bringing it to a sudden and permanent halt. Unwilling to assign the car to a nameless grave in Potter's Field, my father paid to have it hauled to a vocational school. Prince Valiant became a vehicular cadaver; the old thing may even have become an organ donor. We don't buy new cars. According to my dad, "You never know what might go wrong with a new car, and you could get a lemon." I say, "But we know even less about a used car. People don't sell their cars when everything's fine. They sell them when things start going wrong." ... ...car key. My dad, the guy with the soft spot for homeless old cars in need of a square meal and a soft bed, had made good on a long-standing promise of "a decent car." It took him six months of scouring the ads, but he'd bought me a car that's only five years old. It's an Acura Legend and appears to be in excellent health. The leather seats are as comfortable as the Peugeot's, no gremlins live in the CD player, and the AC and heating systems have no viruses. The sunroof is dry as a bone, and the car starts whenever I turn the key. Overall, I'd say the car has a superb attitude. That first morning of new ownership, I stood staring in awe at this white beauty. Then the rest of my life spread before me as my father said, "And we can give it to Bria when she starts driving. It should have all the bugs worked out of it by then." Bria is my five-year-old niece.

Thursday, October 24, 2019

In class Assignment

The point in the issue is that the common understanding of the idea and language is efferent in different cultures. Thus all the companies should mix up different culture people so people can understand different cultures. In the Bell's example illustrates the different cultural thinking where pantomime tradition and since ancient times in plays leading man is being played by lady and vice-versa wherein American people thought that all these people enjoying are freaks and the play is politically incorrect.As in nonverbal communication is considered in Indian culture while greeting people put their hands together with a slightly bow of their head and saying â€Å"Names† which wows respect amongst each other while in Western culture while greeting people is quite important to shake hands, make an eye contact and kiss on checks is necessary.When a company has definite values of business which would lead to equality amongst employees belonging to different cultures the communicati on would be difficult amongst everybody and people would not be able to reach an expectation of their colleagues but gradually with the time span goes people would know an individual's perspective, values and beliefs which would help them to build an right expectation further it creates respect amongst employees. So according to me yes it is good idea to grow a company with multicultural environment and let people know other people.Businesses with multicultural people have its advantages and disadvantages. For instance, considering it as an advantage it is useful to for increasing knowledge of different cultures and worldwide involvement which leads a strong base of globalization whereas on other side there are also certain disadvantage of getting along with different cultures as in there can be high risk of discrimination.

Wednesday, October 23, 2019

Crim Justice

Multiple Choice: Chose the most appropriate answer to the following questions: 1. Which of the following had a profound effect on individual rights by the 1980s? a. The Civil Rights movement. b. The Vietnam War. c. Terrorism. d. The increased use of drugs. 2. Which model below best assumes that the system’s components work together harmoniously to achieve justice. a. Due Process Model b. Conflict Model c. Individual Rights Model d. Consensus Model 3. Which step in the pretrial activities does a judicial officer determine if a crime has been committed? . Indictment b. Information c. Preliminary Hearing d. Information 4. According to the author Race and Ethnicity are buzz words that people use when discussing: a. Religion b. Fourth Amendment c. Multiculturalism d. Terrorism 5. Which of the following describes the scientific study of the causes and prevention of crime and the rehabilitation and punishment of offenders? a. Incarceration b. Criminology c. Indictment d. multicultura lism 6. Which Amendment to the U. S. Constitution is concerned with the defendant’s right to a jury trial? a. Fourth b. Fifth c. Sixth d. Eighth 7.A(n)________ is defined as criminal proceedings, the examination in court of the issues of fact and relevant law in a case for the purpose of convicting or acquitting the defendant. a. Trial b. Indictment c. Arraignment d. Probable Cause 8. Which of the following refers to crime fighting strategies that have been scientifically tested and are based on social science research? a. Crime Control Model b. Evidence Based Practice c. Social Control Model d. Criminology 9. Which stage in the criminal justice process involves taking pictures and fingerprints of a suspect? a. Arraignment b.Indictment c. Preliminary Hearing d. Booking 10. The first step in the Criminal Justice process begins with the: a. Arrest b. Investigation c. Booking d. Warrant 11. The preliminary hearing is used to decide whether: a. there are reasonable grounds to bel ieve the defendant committed the crime. b. the crime that occurred is a felony. c. the defendant is fit to stand trial. d. the defendant is guilty beyond a reasonable doubt. 12. An ideal that embraces all aspects of civilized life and that is linked to fundamental notions of fairness and to cultural beliefs about right and wrong is known as: . Equal rights b. Social Justice c. Multiculturalism d. Civil Justice 13. Who returns an indictment? a. the prosecutor b. the judge c. the arresting police officer d. the grand jury 14. Multiculturalism is often used in conjunction with what other term? a. traditionalist b. diversity c. homogeneous d. ethnocentric 15. A criminal justice perspective model that emphasizes the efficient arrest and conviction of criminal offenders is known as: a. Social Control Model b. Due Process Model c. Crime Control Model d. Omnibus Bill Model Chapter 1- True-FalseCircle the most appropriate answer to the following questions. 1. The Conflict Model assumes that the criminal justice system’s components function primarily to serve their own interests a. True b. False 2. The Corrections stage begins once a defendant has been convicted, but before sentencing. a. True b. False 3. Due Process is a right guaranteed only found in the Fifth Amendment to the U. S. Constitution. a. True b. False 4. The Crime-controlled model is defined as a criminal justice perspective that emphasizes the efficient arrest and conviction of criminal offenders. a. True . False 5. Gideon v. Wainwright is a landmark U. S. Supreme Court case ensuring the defendant’s right to a jury trial. a. True b. False Chapter 1 – Fill in the Blank Fill in the blank with the word or phrase that best completes or answers the question. 1. Not guilty, guilty, and no contest are all acceptable pleas at the______________. 2. The _________ model of criminal justice assumes that the system’s components function primarily serve their own interests. 3. The __________ model of criminal justice assumes that each of the component parts strive towards a common goal. 4. __________ based practice is crime fighting strategies that have been scientifically tested and are based on social science research. 5. ___________ occurs when there is conduct in violation of the criminal laws of a state, the federal government, or a local jurisdiction for which there is no legally acceptable justification or excuse. Chapter 1 – Matching Match the term in the numbered column with the answer in the lettered column. 1. Preliminary Hearing| a. A formal written accusation submitted to the court by a grand jury alleging that a specified person has committed a specified offense, usually a felony. 2. Indictment| b. A formal written accusation submitted to a court by a prosecutor alleging that a specified person has committed a specified offense. | 3. Probable Cause| c. A proceeding before a judicial officer in which it must be shown that: a crime was committed, the crime occurred within the jurisdiction of the court, and there are reasonable grounds to believe that the defendant did the crime. | 4. Information| d. A set of facts and circumstances that would induce a reasonably intelligent and prudent person to believe that a specified person has committed a specified crime. Chapter 1 Essay Provide detailed and comprehensive information to support your answer. Where applicable use examples to support your answers. 1. What is meant by due process of law? 2. Define multiculturalism, and highlight the importance of multiculturalism to the criminal justice process. 3. Compare and contrast the three main components of the criminal justice system. 4. Discuss the crime fighting strategies that have been scientifically tested and are based on social science research. 5.Define and discuss the term Administration of Justice. Chapter 1 – Critical Thinking Answer each part of the following questions with succinct and comprehensive information by ci ting examples of various models, laws, and justice theories in your answer. 1. Do you see a trend in our society in favor of individual rights or public interests? Cite recent examples to support your position. 2. What does justice mean to you? Discuss the three types of justice and their effect on individual rights to support your answer.